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90
CEM Corporation sax hplc radioactivity elution profiles
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ATCC q tof lc ms intact protein profiling
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National Institute of Standards and Technology gas chromatography-mass spectrometry
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Bio-Rad metal affinity chromatography
Metal Affinity Chromatography, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Bio-Rad gel permeation chromatography profiles
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Spark Holland hplc-ms/ms system
High-performance liquid <t>chromatography–tandem</t> <t>mass</t> <t>spectrometry</t> <t>(HPLC-MS/MS)</t> conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.
Hplc Ms/Ms System, supplied by Spark Holland, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Shimadzu Corporation nexera x2 lc 30ad ultrahigh performance liquid chromatograph
High-performance liquid <t>chromatography–tandem</t> <t>mass</t> <t>spectrometry</t> <t>(HPLC-MS/MS)</t> conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.
Nexera X2 Lc 30ad Ultrahigh Performance Liquid Chromatograph, supplied by Shimadzu Corporation, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Metabo Inc ultraperformance liquid chromatography tandem mass spectrometry
High-performance liquid <t>chromatography–tandem</t> <t>mass</t> <t>spectrometry</t> <t>(HPLC-MS/MS)</t> conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.
Ultraperformance Liquid Chromatography Tandem Mass Spectrometry, supplied by Metabo Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 86 stars, based on 1 article reviews
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SAS institute sas statistical analysis system
High-performance liquid <t>chromatography–tandem</t> <t>mass</t> <t>spectrometry</t> <t>(HPLC-MS/MS)</t> conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.
Sas Statistical Analysis System, supplied by SAS institute, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
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Metrohm AG profic 15–ancat ion chromatograph
High-performance liquid <t>chromatography–tandem</t> <t>mass</t> <t>spectrometry</t> <t>(HPLC-MS/MS)</t> conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.
Profic 15–Ancat Ion Chromatograph, supplied by Metrohm AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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High-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.

Journal: Frontiers in Oncology

Article Title: Integrative Analysis of Pharmacokinetic and Metabolomic Profiles for Predicting Metabolic Phenotype and Drug Exposure Caused by Sotorasib in Rats

doi: 10.3389/fonc.2022.778035

Figure Lengend Snippet: High-performance liquid chromatography–tandem mass spectrometry (HPLC-MS/MS) conditions for the quantitation of sotorasib. (A) Product ion mass spectra and chromatogram of sotorasib and the internal standard (IS; carbamazepine) in ESI + mode. (B) Typical chromatogram of sotorasib (1.46 min) and IS (1.58 min) at the indicated retention times.

Article Snippet: For metabolic profiling analysis, the HPLC-MS/MS system (Spark Holland; API 5500, SCIEX, Concord, Canada) was adopted for targeted metabolomic analysis.

Techniques: High Performance Liquid Chromatography, Mass Spectrometry, Tandem Mass Spectroscopy, Quantitation Assay

Intra- and inter-day accuracy and precision of the  HPLC-MS/MS  method in rat plasma ( n = 6).

Journal: Frontiers in Oncology

Article Title: Integrative Analysis of Pharmacokinetic and Metabolomic Profiles for Predicting Metabolic Phenotype and Drug Exposure Caused by Sotorasib in Rats

doi: 10.3389/fonc.2022.778035

Figure Lengend Snippet: Intra- and inter-day accuracy and precision of the HPLC-MS/MS method in rat plasma ( n = 6).

Article Snippet: For metabolic profiling analysis, the HPLC-MS/MS system (Spark Holland; API 5500, SCIEX, Concord, Canada) was adopted for targeted metabolomic analysis.

Techniques: